15 Aug

New designer viruses can help fight cancer: study

New designer viruses can help fight cancer: study

New designer viruses can help fight cancer: study

Scientists have created artificial “designer” viruses that can target cancer by alerting the body’s immune system and sending killer cells to fight tumors. The findings, published in the journal Nature Communications, could pave the way for new treatments for cancer.

Most cancer cells do not cause a limited response by the immune system – body defense mechanism – and can grow without appreciable resistance. In contrast, viral infections cause the release of warning signals, which stimulates the immune system to use all available means to fight the invader.

Immunotherapies, used to treat cancer for many years “désinhibent” body defense system and thus strengthen your heart fight against cancer cells half way. Stimulate the immune system to specifically fight relentlessly and cancer cells, yet being elusive.

Researchers at the University of Geneva (UNIGE) and the University of Basel in Switzerland have managed to manufacture innovative design viruses for this purpose. They constructed the artificial lymphocytic choriomergic virus based virus (LCM), which can infect humans and rodents.

Although not harmful to mice, they release the warning signs typical of viral infections. The researchers also incorporated certain proteins into the virus that is found differently in cancer cells. The designer’s infection allowed the immune system to recognize these cancer proteins as dangerous.

The unique combination of the warning signals and cancer cell protein stimulated the immune system to create a powerful army of cytotoxic T lymphocytes, also called killer cells, that identify cancer cells through their proteins and were destroyed with the success.

The treatments provided to patients with cancer have developed considerably in recent years. However, as the researchers report, current treatments are still insufficient in the fight against many forms of cancer.

“We hope our new discoveries and technology will soon be used in cancer treatments and thus help increase your success rate,” said Doron Merkler UNIGE.

10 Aug

How to do the Planning , Practice & Preparation of GATE Exam

All technical students on the common program in the first year of his degree. This is also the stage where they have enough time and exposure to explore future prospects in the various fields of engineering, research, public sector, administration, etc. Students should assess their skills and competencies while selecting the area of interest.

A good score in the GATE exam is a good start for students with an interest in the fields of higher education and research and development. The GATE exam tests the basic knowledge, as well as students applied in different fields. Therefore, they should prepare thoroughly, focusing on two aspects of the issues.

Students should assess their skills and competencies while selecting the area of interest. A good score in the GATE exam is a good start for students with an interest in the fields of higher education and research and development. The GATE exam tests the basic knowledge, as well as students applied in different fields. Therefore, they should prepare thoroughly, focusing on two aspects of the issues.

Learning Resources for GATE Exam

It is very important that students choose the appropriate learning resources as a standard text and reference material under the direction of their teachers and mentors. Students must rely on study materials that can be easily understood. If one is willing to participate in coaching classes (but not necessary), it must be done after due diligence and consultation with peer groups. In addition, there are many useful learning resources that are available online.
Almost all GATE exam questions cover derivatives and applications on different systems. Therefore, students must necessarily go for the fundamental and applied concepts of matter.

Minimizing the Stress during the Preparation of GATE Exam

All of the above can be easily achieved without stress with these simple tips:
Focus on the second year’s GATE exam with its usual preparation for the semester review. You can begin by matching the content of the GATE program with their regular program and reach the depth of the subject to a degree that only needs a brush in the future of that part.

You can prepare comprehensive notes taking into account the requirements of the GATE exam. You must follow the same strategy during the third year as well.
At the beginning of last year, you should check their preparation for the GATE exam. You should then set a goal to complete the rest of the program within two or three months, that is until October.
Once you are clear about the program, chalk out a schedule for the completion of the curriculum and in time.
At all stages continue to collect the subject’s cracks, a separate laptop topic that will be useful to remember the important points at a glance.

Advantage of Topics

Use your favorite topics as their competitive advantage to succeed in the GATE exam.
In the final stage of preparation, you should focus on examination and practice. His continued practice in resolving the previous year’s papers will give a good idea of what would be the real role. It also collects the basics and highlights that need improvement. Solving more and more test documents is the best way to continue to improve the preparation of GATE.
By solving the test documents, establishing an environment that simulates the actual test without interruption, without disturbance and a defined time limit. This is a very effective arrangement, which doubles the actual test environment, allowing you to prepare without any tension.

Candidates who aspire to a good score in the GATE exam should plan their studies with their curriculum as usual, and must spend three months of last year of practice perfection in the above questions.

09 Aug

Pakistan terror groups pose threat to our interests in India, Afghanistan: US spy chiefs

Pakistan terror groups pose threat to our interests in India, Afghanistan: US spy chiefs

Pakistan terror groups pose threat to our interests in India, Afghanistan: US spy chiefs

NEW DELHI: The US intelligence community is said to have informed Congress that Pakistan has failed to stop terrorist activities operating from its territory, a Pakistan-based daily Dawn reported.
“… and because of their failure, these (terrorist) groups (continue) will present a continuing threat to US interests in the region and will continue to plan and carry out attacks in India and Afghanistan,” said the report citing Intelligence of the United States.
“During a congressional hearing on Afghanistan and ongoing war against terrorist elements, intelligence chiefs would have given an honest assessment of the situation in Afghanistan to the war-torn Committee of the Senate,” the paper said.
A transcript published this weekend shows that while much of the debate has focused on Pakistan, we express concern that, despite a greater military effort to defeat the Taliban, militants will continue to make gains, especially in areas Rural areas of Afghanistan.
“The performance of the Afghan security forces is likely to increase due to a combination of Taliban operations, combat casualties, defections, poor logistics and weak leadership,” warned National Intelligence Director Dan Coats.
Coats runs a team of more than a dozen spy agencies, including the CIA and the FBI.
Illinois Republican Senator Joni Ernst Kay called on intelligence chiefs to indicate measures Washington would like neighbors to take to Kabul to help stabilize the region.
“I think definitely an assessment of how we work with Pakistan to deal with the situation of hosting terrorist groups would be essential for a strategy that affects Afghanistan,” said M. Coats.
“Because this is a potentially very damaging situation putting our own troops at risk and undermining the strategy to deal with local Taliban groups and try to undermine the government (Afghanistan). It is a very clear link I think I have to address In conjunction with everything that has been done in Afghanistan. ”
“In addition to more troops, whatever plan might be part of the plan we see, we have to implement a different strategy on the ground in Afghanistan.” Ernst Senator asked Lieutenant General of Defense, General Vincent Stewart.
“We have to get some things in. One, very clear, security and stability in Afghanistan is in the interest of all parts of the region and it is safe for Pakistan,” Stewart said.
“We must convince Pakistan that if they receive members of the Haqqani network, they are not interested in continuing to host the Haqqani network.”
Stewart also urged the Trump administration to work with Afghanistan’s neighbors to go after the 20 terrorist organizations remain active in the region.
“They threaten not only Afghanistan, but not just Pakistan, but the entire region,” he added.
Stewart also suggested “pushing” Pakistan to do more against the Haqqani network and urged lawmakers to “separate the Pashtun Taliban” because Pakistan wanted Pakistan-dominated Pashtun.
“So we need to resume the conversation with Pakistan on its part, not to house any of these terrorists, helping to stabilize Afghanistan and, I think, perhaps, we will have progress,” it was said.

“They consider all the challenges through the emergence of a threat from India to the state of Pakistan. So they organize terrorist organizations … so if Afghanistan is based in India, it no longer supports the idea of A stable and secure Afghanistan that could harm the interests of Pakistan, “he said.

02 Aug

PM Modi to hardsell India’s economic reform initiatives in Germany

PM Modi to hardsell India’s economic reform initiatives in Germany

PM Modi to hardsell India’s economic reform initiatives in Germany

BERLIN: Summer has come this year in Berlin. But as temperatures may not reach the heights of Delhi, Prime Minister Narendra Modi is likely to find Germany in the heat of a summer night when he plays + here on Monday night.
On the first of the two scheduled visits this year in Germany – Modi will return to Hamburg in July for the G20 + Summit – the bilateral summit will be launched with a warm dinner with Chancellor Angela Merkel at Schloss-Meseberg, Country Official Chancellor of Retirement. This is a special gesture to point out the importance of the bilateral relationship. This will be the last meeting of Modi-Merkel before Germany does towards the national elections in September.
Merkel warns the United States, Britain, the unreliable partner
In a Facebook message prior to his visit, Modi said: “Our strategic alliance is based on democratic values and a commitment to a global order, based on inclusive and open standards.” Germany is a valuable partner in our development and knowledge initiatives Of German fits well with my vision of transforming India “The continuity of India’s foreign policy is most evident here -. Manmohan Singh and Modi describe the relationship between India and Germany as “transformation”.
Modi and Merkel will convene a group of top leaders here today that Modi’s economic reform initiatives in India are expected to stand out and invite them to invest in India. The problem in this case, from the German point of view, is India’s decision to kill the entire bilateral investment treaty between India and European countries.
Indian authorities said the treaties were badly negotiated and clearly against the interests of India. European countries have asked India to hold for six more months, but India refused, anticipating that European countries weigh heavily with the EC to complete free-trade talks between India and EU. Discussions on the FTA have been delayed and will continue to be the fact that the EU is currently consumed with the Brexit negotiations.
Meanwhile, India has circulated a text of the model investment treaty, which is useless to the European countries that have given this power in Brussels. In the absence of the ILO, German officials said there were no new investments in India that would affect their decisions

Modi must convince them that investment in India will benefit from protections.
Away, Modi said:. “On May 30, Chancellor Merkel and I will conduct the fourth IGC to examine the state of our bilateral relations, also described future cooperation Roadmap oriented to trade and investment, security and counter-terrorism , Innovation and science and technology, skills development, urban infrastructure, railways and civil aviation, clean energy, development cooperation, health and alternative medicine. ” The Indian firm closed an agreement with Germany last week on cooperation in traditional medicine.